منابع مشابه
Hyperkalemia-induced complete heart block
Background: Potassium, as an extracellular ion, plays an important role in the electrophysiologic function of the myocardium and any change in extracellular concentration of this ion might have a marked impression upon myocyte electrophysiologic gain. High serum potassium levels are thought to impair pulse conduction in Purkinje fibers and ventricles more than that in the Atrio...
متن کاملAutoimmunity in Chagas heart disease.
The possibility that cardiac autoimmunity contributes to the pathogenesis of Chagas heart disease is controversial. In this paper, we address the following questions regarding the genesis of autoimmunity in Chagas heart disease: (i) What mechanism(s) are potentially responsible for the generation of self-directed antibodies and lymphocytes? (ii) What is the evidence that any of these mechanisms...
متن کاملRheumatic Heart Disease: Genes, Inflammation and Autoimmunity
Rheumatic heart disease is a sequel of rheumatic fever that follows an untreated group A streptococcal infection in young susceptible individuals. The disease is mediated by autoimmune reactions. Several genes related to both the innate and adaptive immune response are involved. Several HLA class II alleles have been associated with the disease. In the present review, we focus on punctual genet...
متن کاملhyperkalemia-induced complete heart block
background: potassium, as an extracellular ion, plays an important role in the electrophysiologic function of the myocardium and any change in extracellular concentration of this ion might have a marked impression upon myocyte electrophysiologic gain. high serum potassium levels are thought to impair pulse conduction in purkinje fibers and ventricles more than that in the atrioventricular (av) ...
متن کاملPolymyositis and complete heart block.
The development of complete heart block is described in a patient with polymyositis. The implantation of a permanent pacemaker has controlled the heart block, but the progression of the underlying disease despite treatment with relatively high dosage of corticosteroids makes the outlook uncertain.
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ژورنال
عنوان ژورنال: BMJ
سال: 1976
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.6001.93